Tianzhi Yang

Profile Picture of Tianzhi Yang
Title
Professor
Department
Department of Pharmaceutical Sciences
Institution
Husson University

Education

  • PhD in Pharmaceutical Sciences, Peking University Health Sciences Center

Research Interests

Gene Delivery   Brain Disorder   Lung Diseases  

  View all research interests

Biography

Not mentioned yet

Homepages

Contact Information

  School of Pharmacy Husson University 1 College Circle Bangor, ME 04401

  2079921946

Research
Not mentioned yet. (?)
List of Publications (59)
In 2020
59

Lu M, Xing H, Cheng L, Liu H, Lang L, Yang T, Zhao X, Xu H, Ding P. A Dual-Functional Buformin-Mimicking Poly(amido Amine) for Efficient and Safe Gene Delivery. Journal of Drug Targeting. 2020 Apr 21; 1-10. doi: 10.1080/1061186X.2020.1729770. Online ahead of print.

Found on Publication Text
In 2019
58

Yang T, Shin HJ, Nguyen K, Bai S (2019). Validation of Stability of Paracetamol in Extemporaneously Compounded Suppositories. Journal of Pharmacy Practice and Research, 49: 219-223.

Found on Publication Text
57

Xing H, Lu M, Yang T, Liu H, Sun Y, Zhao X, Xu H, Yang L, Ding P (2019). Structure-function relationships of nonviral gene vectors: Lessons from antimicrobial polymers. Acta Biomaterialia, 86:15-40.

Found on Publication Text
56

Sun Y, Liu H, Yang T, Lang L, Cheng L, Xing H, Yang L, Ding P (2019). Amphoteric poly(amido amine)s with adjustable balance between transfection efficiency and cytotoxicity for gene delivery. Colloids and Surface B: Biointerfaces, 175:10-17.

Found on Publication Text
55

Lu M, Zhao X, Xing H, Liu H, Lang L, Yang T, Xun Z, Wang D, Ding P (2019). Cell-free synthesis of connexin 43-integrated exosome-mimetic nanoparticles for siRNA delivery. Acta Biomater, 96:517-536.

Found on Publication Text
54

Liu H, Sun Y, Lang L, Yang T, Zhao X, Cai C, Liu Z, Ding P (2019). Nuclear localization signal peptide enhances transfection efficiency and decreases cytotoxicity of poly(agmatine/N, N'-cystamine-bis-acrylamide)/pDNA complexes. Journal of Cell biochemistry, 120:16967-16977.

Found on Publication Text
53

Liu H, Zhen Y, Zhe X, Gao Z, Sun Y, Yu J, Yang T, Zhao X, Cai C, Ding P (2019). Nuclear delivery of plasmid DNA determines the efficiency of gene expression. Cell Biology International, 43: 789-798.

Found on Publication Text
52

Xing H, Cheng L, Lu M, Liu H, Lang L, Yang T, Zhao X, Xu H, Yang L, Ding P (2019). A biodegradable poly(amido amine) based on the antimicrobial polymer polyhexamethylene biguanide for efficient and safe gene delivery. Colloids Surf B Biointerfaces, 182:110355. doi: 10.1016/j.colsurfb.2019.110355.

Found on Publication Text
In 2018
51

Yang T, Mustafa F, Bai S, Ahsan F (2004). Pulmonary delivery of low molecular weight heparins. Pharmaceutical Research, 21: 2011-2018.

Found on Publication Text
50

Yang T, Ferrill L, Gallant L, McGillicuddy S, Fernandes T, Schields N, Bai S (2018). Verapamil and riluzole cocktail liposomes overcome pharmacoresistance by inhibiting P-glycoprotein in brain endothelial and astrocyte cells: A potent approach to treat amyotrophic lateral sclerosis. European Journal of Pharmaceutical Sciences, 120: 30-39.

Found on Publication Text
49

Lu M, Zhao X, Xing H, Xun Z, Zhu S, Lang L, Yang T, Cai C, Wang D, Ding P (2018). Comparison of exosome-mimicking liposomes with conventional liposomes for intracellular delivery of siRNA. International Journal of Pharmaceutics, 550:100-113.

Found on Publication Text
48

Sun Y, Liu H, Xing H, Lang L, Chen L, Yang T, Yang L, Ding P (2018). Bioreducible poly(amido amine) copolymers derived from histamine and agmatine for highly efficient gene delivery. Polymer International, 68: 447-455.

Found on Publication Text
47

Lu M, Xing H, Xun Z, Yang T, Zhao X, Cai C, Wang D, Ding P (2018). Functionalized extracellular vesicles as advanced therapeutic nanodelivery systems. European Journal of Pharmaceutical Sciences, 121: 34-46.

Found on Publication Text
46

Lu M, Xing H, Xun Z, Yang T, Ding P, Cai C, Wang D, Zhao X (2018). Exosome-based small RNA delivery: Progress and prospects. Asian Journal of Pharmaceutical Sciences, 13: 1-11.

Found on Publication Text
45

Zhang J, Wang C, Lu M, Xing H, Yang T, Cai C, Zhao X, Wei M, Yu J, Ding P (2018). Intracellular distribution and internalization pathways of guanidinylated bioresponsive poly(amido amine)s in gene delivery. Asian Journal of Pharmaceutical Sciences, 13: 360-372.

Found on Publication Text
44

Lu M, Zhao X, Xing H, Xun Z, Yang T, Cai C, Wang D, Ding P (2018). Liposome-chaperoned cell-free synthesis for the design of proteoliposomes: Implications for therapeutic delivery. Acta Biomaterialia, 18: S1742-706.

Found on Publication Text
43

Yang Z, Sun Y, Xian L, Xun Z, Yu J, Yang T, Zhao X, Cai C, Wang D, Ding P (2018). Disulfide-bond-containing agamatine-cystaminebisacrylamide polymer demonstrates better transfection efficiency and lower cytotoxicity than polyethylenimine in NIH/3T3 cells. Journal of Cell Biochemistry, 119:1767-1779.

Found on Publication Text
42

Sun Y, Liu H, Cheng L, Zhu S, Cai C, Yang T, Yang L, Ding P (2018). Thiol Michael addition reaction: a facile tool for introducing peptides into polymer-based gene delivery systems. Polymer International, 67: 25-31.

Found on Publication Text
In 2017
41

Yang T, Fogarty B, LaForge B, Aziz1 S, Pham T, Lai L, Bai S (2017). Delivery of small interfering RNA to inhibit vascular endothelial growth factor in zebrafish using natural brain endothelia cell-secreted exosome nanovesicles for the treatment of brain cancer. The AAPS Journal, 19: 475-486.

Found on Publication Text
40

Yang T, Tran D, Lai L, Bai S (2017). Zebrafish (Danio Rerio) in Modeling Brain Disorders. Annals of Pharmacology and Pharmaceutics 2: 1037-42.

Found on Publication Text
39

Sun Y, Yang Z, Wang C, Yang T, Cai C, Zhao X, Yang L, Ding P (2017). Exploring the role of peptides in polymer-based gene delivery. Acta Biomaterialia, 60: 23-37.

Found on Publication Text
38

Lu M, Xing H, Yang Z, Sun Y, Yang T, Zhao X, Cai C, Wang D, Ding P (2017). Recent advances on extracellular vesicles in therapeutic delivery: Challenges, solutions, and opportunities. European Journal of Pharmaceutics and Biopharmaceutics, 119: 381-395.

Found on Publication Text
37

Zhang J, Yu J, Jiang J, Chen X, Sun Y, Yang Z, Yang T, Cai C, Zhao X, Ding P (2017). Uptake pathways of guanidinylated disulfide containing polymers as nonviral gene carrier delivering DNA to cells. Journal of Cellular Biochemistry, 18: 903-913.

Found on Publication Text
36

Lu M, Xing H, Yang T, Yu J, Yang Z, Sun Y, Ding P (2017). Dissolution enhancement of tadalafil by liquisolid technique. Pharmaceutical Development and Technology, 22: 77-89.

Found on Publication Text
35

Lu M, Xing H, Jiang J, Chen X, Yang T, Wang D, Ding P (2017). Liquisolid technique and its applications in pharmaceutics, Asian Journal of Pharmaceutical Sciences, 12: 115-123.

Found on Publication Text
34

Sun Y, Xian L, Yu J, Yang T, Zhang J, Yang Z, Jiang J, Cai C, Zhao X, Yang L, Ding P (2017). Structure-function correlations of poly(amido amine)s for gene delivery. Macromolecular Bioscience, 17: 1-16.

Found on Publication Text
33

Yang T, Martin P, Fogarty B, Brown A, Schurman K, Phipps R, Yin V, Lockman P, Bai S (2015). Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio Rerio. Pharmaceutical Research, 32: 2003-2014 (2017 Meritorious Manuscript Award).

Found on Publication Text
In 2016
32

Yu J, Zhang J, Xing H, Sun Y, Yang Z, Yang T, Cai C, Zhao X, Yang L, Ding P (2016). Novel guanidinylated bioresponsive poly(amidoamine)s designed for short hairpin RNA delivery. International Journal of Nanomedicine, 11: 6651-6666.

Found on Publication Text
31

Lu M, Xing H, Chen X, Xian L, Jiang J, Yang T, Ding P (2016). Advance in bioequivalence assessment of topical dermatological products. Asian Journal of Pharmaceutical Sciences, 11: 700-707.

Found on Publication Text
30

Sun Y, Xian L, Xing H, Yu J, Yang Z, Yang T, Yang L, Ding P (2016). Factors influencing the nuclear targeting ability of nuclear localization signals. Journal of Drug Targeting, 24: 927-933.

Found on Publication Text
In 2014
29

Yang T, Bantegui T, Pike K, Bloom R, Phipps R, Bai S (2014). In Vitro evaluation of optimized liposomes for delivery of small interfering RNA. Journal of Liposome Research, 24: 270-279.

Found on Publication Text
28

Zhu Z, Yang T, Zhao Y, Gao N, Leng D, Ding P (2014). A simple method to improve the dissolution of repaglinide and exploration of its mechanism. Asian Journal of Pharmaceutical Sciences, 9: 218-225.

Found on Publication Text
27

Gao Q, Zhao Y, Yu J, Yang T, Ding P (2014). Microdialysis as a tool to determine the skin concentration of mometasone Furoate in rats. Pharmazie, 69: 787-791.

Found on Publication Text
In 2012
26

Yang T, Nyiawung D, Silber A, Hao J, Lai L, Bai S (2012). Comparative studies on chitosan and polylactic-co-glycolic acid incorporated nanoparticles of low molecular weight heparin, AAPS PharmSciTech, 13: 1309-1318.

Found on Publication Text
In 2010
25

Paulson JR*, Yang T*, Selvaraj PK, Mdzinarishvili A, Van der Schyf CJ, Klein J, Bickel U, Abbruscato TJ (2010). Nicotine exacerbates brain edema during in vitro and in vivo focal ischemic conditions. Journal Pharmacology Experimental Therapeutics, 332:371-379 (*, Equal contribution).

Found on Publication Text
In 2009
24

Vemula S, Roder KE, Yang T, Bhat GJ, Thekkumkara TJ, Abbruscato TJ (2009). A functional role for sodium dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation. Journal Pharmacology Experimental Therapeutics, 328: 487-495.

Found on Publication Text
In 2008
23

Rawat A*, Yang T*, Hussain A, Ahsan F (2008). Complexation of a Poly-L-Arginine with low molecular weight heparin enhances pulmonary absorption of the drug. Pharmaceutical Research, 25: 936-948 (*, Equal contribution).

Found on Publication Text
22

Bai S, Yang T, Abbruscato TJ, Ahsan F (2008). Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies. Journal of Pharmaceutical Sciences, 97: 1165-1178.

Found on Publication Text
In 2007
21

Yang T, Roder KE, Abbruscato TJ (2007). Evaluation of bEnd5 cell line as an in vitro model for the blood-brain barrier under normal and hypoxic/aglycemic conditions. Journal of Pharmaceutical Sciences, 96: 3196-3123.

Found on Publication Text
In 2006
20

Yang T, Hussain A, Bai S, Khalil IA, Harashima H, Ahsan F (2006). Positively charged polyethylenimines enhance nasal absorption of the negatively charged drug, low molecular weight heparin. Journal of Controlled Release, 115: 289-297.

Found on Publication Text
19

Yang T, Roder KE, Bhat GJ, Thekkumkara TJ, Abbruscato TJ (2006). Protein kinase C family members as a target for regulation of blood-brain barrier Na, K, 2Cl-cotransporter during in vitro stroke conditions and nicotine exposure. Pharmaceutical Research, 23: 291-301.

Found on Publication Text
In 2005
18

Yang T, Arnold JJ, Ahsan F (2005). Tetradecylmaltoside (TDM) enhances the in vitro and in vivo intestinal absorption of enoxaparin, a low molecular weight heparin. Journal of Drug Targeting, 13: 29-38.

Found on Publication Text
In 2004
17

Yang T, Mustafa F, Ahsan F (2004). Alkanoylsucroses in nasal delivery of low molecular weight heparins: in-vivo absorption and reversibility studies in rats. Journal of Pharmacy and Pharmacology, 56: 53-60.

Found on Publication Text
16

Yang T, Hussain A, Ahsan F (2004). Cyclodextrins in nasal delivery of low molecular weight heparins: in vivo and in vitro studies. Pharmaceutical Research, 21: 1127-1136.

Found on Publication Text
15

Mustafa F, Yang T, Khan MA, Ahsan F (2004). Chain length dependent effects of alkylmaltosides on nasal absorption of enoxaparin, Journal of Pharmaceutical Sciences, 93: 675-683.

Found on Publication Text
In 2003
14

Hussain A, Yang T, Zaghloul A, Ahsan F (2003). Pulmonary absorption of insulin mediated by tetradecyl--maltoside and dimethyl--cyclodextrin. Pharmaceutical Research, 20: 1551-1557.

Found on Publication Text
13

Ahsan F, Arnold JJ, Yang T, Schiewbert E, Meezan E, Pillion DJ (2003). Effects of the permeability enhancers, tetradecylmaltoside and dimethyl--cyclodextrin, on insulin movement across human bronchial epithelial cells (16HBE14o-). European Journal of Pharmaceutical Sciences, 20: 27-34.

Found on Publication Text
12

Yang T, Chen Q, Chen D, Zhang Q (2003). Pharmacodynamic and pharmacokinetic studies of an insulin buccal spray formulation in rats and rabbits. Chinese Pharmaceutical Journal, 38: 448-452.

Found on Publication Text
In 2002
11

Yang T, Wang X, Yan X, Zhang Q (2002). Phospholipid deformable vesicles for buccal delivery of insulin. Chemical and Pharmaceutical Bulletin, 50: 749-753.

Found on Publication Text
10

Yang T, Wang X, Chen D, Zhang Q (2002). Pharmacodynamics and pharmacokinetics of the insulin buccal spray formulation in rabbits. Asian Journal of Drug Metabolism and Pharmacokinetics, 2: 29-35.

Found on Publication Text
9

Yang T, Chen D, Chen Q, Zhang Q (2002). Effect of enzymes in buccal mucous membrane on buccal absorption of insulin. Journal of Chinese Pharmaceutical Sciences, 11: 28-33.

Found on Publication Text
8

Yang T, Chen D, Wang L, Zhang Q (2002). Effect of enzymes in buccal mucosa on insulin buccal absorption. Acta Pharmaceutica Sinica, 36: 932-936.

Found on Publication Text
7

Yang T, Wang X, Yan X, Zhang Q (2002). Studies on buccal delivery of insulin flexible nanoliposomes. Acta Pharmaceutica Sinica, 37: 885-891.

Found on Publication Text
6

Chen D, Yang T, Lu W, Zhang Q (2002). In vitro and in vivo study of two kinds of long circulating solid lipid nanoparticles containing paclitaxel. Acta Pharmaceutica Sinica, 37: 54-58.

Found on Publication Text
5

Chen D, Lu W, Yang T, Li J, Zhang Q (2002). Preparation and characterization of long-circulating solid lipid nanoparticles containing paclitaxel. Journal of Peking University Health Sciences, 34: 57-60.

Found on Publication Text
4

Wang X, Yang T, Li S, Hou X (2002). Liposome preparation by saturated phospholipid at room temperature and properties of the liposomes. Acta Pharmaceutica Sinica, 37: 976-980.

Found on Publication Text
In 2001
3

Yang T, Chen D, Zhang Q (2001). Comparison of the effects of various absorption enhancers and enzyme inhibitors on buccal insulin delivery in vitro and in vivo. Journal of Peking University Health Sciences, 33: 238-242.

Found on Publication Text
2

Chen D, Yang T, Lu W, Zhang Q (2001). In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. Chemical and Pharmaceutical Bulletin, 49: 1444-1447.

Found on Publication Text
1

Yang T, Zhang Q, Chen D, Nagai T (2001). Comparison of the effects of various transmucosal absorption enhancers on buccal insulin delivery: in vitro and in vivo studies. STP Pharma Sciences, 11: 415-419.

Found on Publication Text
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