Research
Brain Organoids
Autism Spectrum Disorder, Autism Spectrum Disorders
Single Cell Transcriptomics, Single Cell Transcriptomes
Direct Reprogramming
Midbrain Dopaminergic Neurons
Stem Cells, Stem Cell
Cell Lines, Cell Line
Single Cell Profiling
Specific Targets, Specific Targeting
D Printing, D Printed
Precise Patterning
Self Assembly
Human Adult
Intracerebral Injection
Viral Vectors
Human Fetal
List of Publications (21)
In 2024
21
Atamian A, Birtele M, Hosseini N, Nguyen T, Seth A, Del Dosso A, Paul S, Tedeschi N, Taylor R, Coba MP, Samarasinghe R, Lois C, Quadrato G. "Human cerebellar organoids with functional Purkinje cells." (2024)
Found on Publication Page
In 2023
20
Urenda JP, Del Dosso A, Birtele M, Quadrato G. "Present and Future Modeling of Human Psychiatric Connectopathies With Brain Organoids." (2023)
Found on Publication Page
19
Birtele M, Del Dosso A, Xu T, Nguyen T, Wilkinson B, Hosseini N, Nguyen S, Urenda JP, Knight G, Rojas C, Flores I, Atamian A, Moore R, Sharma R, Pirrotte P, Ashton RS, Huang EJ, Rumbaugh G, Coba MP, Quadrato G. "Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis." (2023)
Found on Publication Page
In 2022
18
Sozzi E, Kajtez J, Bruzelius A, Wesseler MF, Nilsson F, Birtele M, Larsen NB, Ottosson DR, Storm P, Parmar M, Fiorenzano A. "Silk scaffolding drives self-assembly of functional and mature human brain organoids." (2022)
Found on Publication Page
17
Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. "Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain." (2022)
Found on Publication Page
16
Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, Ottosson DR, Falk A, Jakobsson J, Barker RA, Parmar M. "Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease." (2022)
Found on Publication Page
15
Kajtez J, Wesseler MF, Birtele M, Khorasgani FR, Rylander Ottosson D, Heiskanen A, Kamperman T, Leijten J, Martinez-Serrano A, Larsen NB, Angelini TE, Parmar M, Lind JU, Emneus J. "Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs." (2022)
Found on Publication Page
13
Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emneus J, Ottosson DR, Storm P, Parmar M. "Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids." (2022)
Found on Publication Page
In 2021
12
Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emneus J, Ottosson DR, Storm P, Parmar M. "Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids." (2021)
Found on Publication Page
11
Kajtez J, Buchmann S, Vasudevan S, Birtele M, Rocchetti S, Pless CJ, Heiskanen A, Barker RA, Martinez-Serrano A, Parmar M, Lind JU, Emneus J. "3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices." (2021)
Found on Publication Page
10
Fiorenzano A, Birtele M, Wahlestedt JN, Parmar M. "Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons." (2021)
Found on Publication Page
9
Nilsson F, Storm P, Sozzi E, Hidalgo Gil D, Birtele M, Sharma Y, Parmar M, Fiorenzano A. "Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation." (2021)
Found on Publication Page
In 2020
8
Nolbrant S, Giacomoni J, Hoban DB, Bruzelius A, Birtele M, Chandler-Militello D, Pereira M, Ottosson DR, Goldman SA, Parmar M. "Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons." (2020)
Found on Publication Page
7
Kajtez J, Buchmann S, Vasudevan S, Birtele M, Rocchetti S, Pless CJ, Heiskanen A, Barker RA, Martinez-Serrano A, Parmar M, Lind JU, Emneus J. "3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices." (2020)
Found on Publication Page
6
Tiklova K, Nolbrant S, Fiorenzano A, Bjorklund AK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lunden-Miguel H, Volakakis N, Kirkeby A, Perlmann T, Parmar M. "Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease." (2020)
Found on Publication Page
5
Tiklova K, Nolbrant S, Fiorenzano A, Bjorklund AK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lunden-Miguel H, Volakakis N, Kirkeby A, Perlmann T, Parmar M. "Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease." (2020)
Found on Publication Page
In 2019
4
Birtele M, Sharma Y, Kidnapillai S, Lau S, Stoker TB, Barker RA, Rylander Ottosson D, Drouin-Ouellet J, Parmar M. "Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons." (2019)
Found on Publication Page
3
Pereira M, Birtele M, Rylander Ottosson D. "In Vivo Direct Reprogramming of Resident Glial Cells into Interneurons by Intracerebral Injection of Viral Vectors." (2019)
Found on Publication Page
2
Pereira M, Birtele M, Rylander Ottosson D. "Direct reprogramming into interneurons: potential for brain repair." (2019)
Found on Publication Page
In 2017
1
Pereira M, Birtele M, Shrigley S, Benitez JA, Hedlund E, Parmar M, Ottosson DR. "Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons." (2017)
Found on Publication Page
