Research
Donor Age
Interorgan Communication
Tissue Engineering
Liver Disease, Liver Diseases
Disease Modeling, Disease Model
Heart Disease
Composite Allografts
Tissue Scaffolds
Large Scale Expansion
Age Dependent Changes
Concept Study
Organ Repair
Myocardial Infarction
Pluripotent Stem Cells, Pluripotent Stem Cell
Stem Cell Fate
Oxidative Stress
Breast Cancer Growth
Human Ipsc, Human Ipscs
Personalized Medicine
Transcriptome Profiling, Transcriptomic Profiling, Transcriptome Profiles
List of Publications (28)
In 2024
28
Optimized Decellularization of a Porcine Fasciocutaneaous Flap. E Lupon, A Acun, CB Taveau, R Oganesyan, HH Lancia, AR Andrews, ... Bioengineering 11 (4), 321, 2024.
Found on Publication Page
In 2023
27
Acellular nipple scaffold development, characterization, and preliminary biocompatibility assessment in a swine model. RV Oganesyan, AG Lellouch, A Acun, E Lupon, CB Taveau, LC Burlage, ... Plastic and Reconstructive Surgery 151 (4), 618e-629e, 2023.
Found on Publication Page
In 2022
26
A reliable porcine fascio-cutaneous flap model for vascularized composite allografts bioengineering studies. V Pozzo, G Romano, M Goutard, E Lupon, P Tawa, A Acun, AR Andrews, ... JoVE (Journal of Visualized Experiments), e63557, 2022.
Found on Publication Page
25
Engineering vascularized composite allografts using natural scaffolds: a systematic review. E Lupon, AG Lellouch, A Acun, AR Andrews, R Oganesyan, M Goutard, ... Tissue Engineering Part B: Reviews 28 (3), 677-693, 2022.
Found on Publication Page
24
Human-origin iPSC-based recellularization of decellularized whole rat livers. A Acun, R Oganesyan, M Jaramillo, ML Yarmush, BE Uygun Bioengineering 9 (5), 219, 2022.
Found on Publication Page
23
Combinatorial Use of Therapeutic ELP Based Micelle Particles in Tissue Engineering. B Bulutoglu, A Acun, SL Deng, S Mert, E Lupon, AG Lellouch, ... Advanced healthcare materials 11 (13), 2102795, 2022.
Found on Publication Page
In 2021
22
Liver donor age affects hepatocyte function through age-dependent changes in decellularized liver matrix. A Acun, R Oganesyan, K Uygun, H Yeh, ML Yarmush, BE Uygun Biomaterials 270, 120689, 2021.
Found on Publication Page
21
REENDOTHELIALIZATION OF DECELLULARIZED SWINE FASCIOCUTANEOUS FLAP: A PROOF-OF-CONCEPT STUDY. V Pozzo, A Acun, E Lupon, R Oganesyan, G Romano, M Goutard, ... XENOTRANSPLANTATION 28 (5), 2021.
Found on Publication Page
20
QS9: Decellularization Of Vascularized Composite Allografts In The Rat. E LUPON, A Acun, M Goutard, AG Lellouch, R Oganesyan, AR Andrews, ... Plastic and Reconstructive Surgery-Global Open 9 (7S), 29-30, 2021.
Found on Publication Page
19
Decellularized liver extracellular matrix for iPSC-based liver engineering. A Acun, BE Uygun Methods in iPSC Technology, 101-121, 2021.
Found on Publication Page
18
Steatotic livers for transplantation: improving utilization of a prevalent resource through organ repair. S Raigani, A Acun, B Uygun, K Uygun, H Yeh Organ Repair and Regeneration, 247-256, 2021.
Found on Publication Page
In 2020
17
Tissue scaffolds functionalized with therapeutic elastin like biopolymer particles. B Bulutoglu, J Devalliere, SL Deng, A Acun, SS Kelangi, BE Uygun, ... Biotechnology and bioengineering 117 (5), 1575-1583, 2020.
Found on Publication Page
16
Decellularization of Vascularized Engineered Scaffolds for Facial Reconstruction. E Lupon, A Acun, MP Goutard, R Oganesyan, AG Lellouch, LA Lantieri, ... Plastic Surgery 2020 (October 16--19, 2020), 2020.
Found on Publication Page
15
Development and Characterization of Decellularized Whole Human Livers for Increasing Donor Pool. A Acun, R Oganesyan, BE Uygun AMERICAN JOURNAL OF TRANSPLANTATION 20, 610-610, 2020.
Found on Publication Page
In 2019
14
In vitro aged, hiPSC-origin engineered heart tissue models with age-dependent functional deterioration to study myocardial infarction. A Acun, TD Nguyen, P Zorlutuna Acta biomaterialia 94, 372-391, 2019.
Found on Publication Page
13
Liver bioengineering: promise, pitfalls, and hurdles to overcome. A Acun, R Oganesyan, BE Uygun Current transplantation reports 6, 119-126, 2019.
Found on Publication Page
12
CRISPR/Cas9 edited induced pluripotent stem cell-based vascular tissues to model aging and disease-dependent impairment. A Acun, P Zorlutuna Tissue Engineering Part A 25 (9-10), 759-772, 2019.
Found on Publication Page
In 2018
11
Hollow microcarriers for large scale expansion of anchorage dependent cells in a stirred bioreactor. A YekrangSafakar, A Acun, JW Choi, E Song, P Zorlutuna, K Park Biotechnology and bioengineering 115 (7), 1717-1728, 2018.
Found on Publication Page
10
Interdependence theory of tissue failure: bulk and boundary effects. D Suma, A Acun, P Zorlutuna, DC Vural Royal Society open science 5 (2), 171395, 2018.
Found on Publication Page
9
Aged, Human-origin Engineered Myocardium Model to Study Reperfusion. A Acun University of Notre Dame, 2018.
Found on Publication Page
In 2017
8
Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine. BW Ellis, A Acun, UI Can, P Zorlutuna Biomicrofluidics 11 (2), 2017.
Found on Publication Page
7
A tissue engineered model of aging: interdependence and cooperative effects in failing tissues. A Acun, DC Vural, P Zorlutuna Scientific reports 7 (1), 5051, 2017.
Found on Publication Page
6
3D hydrogel-based microwell arrays as a tumor microenvironment model to study breast cancer growth. J Casey, X Yue, TD Nguyen, A Acun, VR Zellmer, S Zhang, P Zorlutuna Biomedical Materials 12 (2), 025009, 2017.
Found on Publication Page
5
Engineered myocardium model to study the roles of HIF-1 and HIF1A-AS1 in paracrine-only signaling under pathological level oxidative stress. A Acun, P Zorlutuna Acta biomaterialia 58, 323-336, 2017.
Found on Publication Page
4
Transcriptome profiling of 3D co-cultured cardiomyocytes and endothelial cells under oxidative stress using a photocrosslinkable hydrogel system. X Yue, A Acun, P Zorlutuna Acta biomaterialia 58, 337-348, 2017.
Found on Publication Page
In 2016
3
Determining Stem Cell Fate with Hydrogels. A Acun, A Panzo, P Zorlutuna GELS HANDBOOK: Fundamentals, Properties and Applications Volume 2 ..., 2016.
Found on Publication Page
In 2014
2
Construction of a collagen-based, split-thickness cornea substitute. A Acun, V Hasirci Journal of Biomaterials Science, Polymer Edition 25 (11), 2014.
Found on Publication Page
Unspecified
1
Effect of Donor Age and Liver Steatosis on Potential of Decellularized Liver Matrices to Be Used as A Platform for Ipsc Hepatocyte Culture. A Acun, L Fan, R Oganesyan, KM Uygun, H Yeh, ML Yarmush, BE Uygun Advanced Healthcare Materials, 2302943, 0.
Found on Publication Page