Research
Mechanosensitive Ion Channels
Biochemistry
Chemistry
Mechanosensitive Channels
MscS
MscL
Escherichia Coli
Gene Expression
Bacterial Genomes
Box Model
Open State
Mechanical Stress
Structure Function
Experimental Verification
List of Publications (24)
In 2021
24
Exploring How Varying Growth Conditions Affect the Gene Expression of Mechanosensitive Ion Channels in Escherichia coli. SC Johnson, HR Malcolm Biophysical Journal 120 (3), 234a, 2021.
Found on Publication Page
23
Exploring the effects of various growth conditions on gene expression of mechanosensitive ion channels in Escherichia coli. SC Johnson, HR Malcolm .
Found on Publication Page
22
Exploring the diversity of mechanosensitive channels in bacterial genomes. SC Johnson, J Veres, HR Malcolm European Biophysics Journal 50, 25-36, 2021.
Found on Publication Page
In 2020
21
Characterizing the mechanosensitive response of Paraburkholderia graminis membranes. BL Miller, HM Dickinson, B Wingender, A Mikhaylova, HR Malcolm Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (4), 183176, 2020.
Found on Publication Page
20
Mechanosensitive Channels in Paraburkholderia Graminis. BL Miller, HR Malcolm Biophysical Journal 118 (3), 13a, 2020.
Found on Publication Page
In 2019
19
Understanding the pH modulation in the E. coli mechanosensitive channel of small conductance (MscS). H Dickinson, B Miller, H Malcolm ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019.
Found on Publication Page
18
Functionally Identifying Members of the MscS Superfamily of Ion Channels in Paraburkholderia Membranes. HM Dickinson, BL Miller, HR Malcolm Biophysical Journal 116 (3), 240a-241a, 2019.
Found on Publication Page
In 2017
17
Exploring the pH Sensitivity of E. Coli MscS. J Veres, HR Malcolm Biophysical Journal 112 (3), 310a, 2017.
Found on Publication Page
In 2015
16
The mechanosensitive channel of small conductance (MscS) functions as a Jack-in-the box. HR Malcolm, P Blount, JA Maurer Biochimica Et Biophysica Acta (BBA)-Biomembranes 1848 (1), 159-166, 2015.
Found on Publication Page
15
Mutations in a conserved domain of E. coli MscS to the most conserved superfamily residue leads to kinetic changes. HR Malcolm, P Blount PloS one 10 (9), e0136756, 2015.
Found on Publication Page
In 2014
14
Heteromultimerization of prokaryotic bacterial cyclic nucleotide-gated (bCNG) ion channels, members of the mechanosensitive channel of small conductance (MscS) superfamily. HR Malcolm, YY Heo, DE Elmore, JA Maurer Biochemistry 53 (51), 8005-8007, 2014.
Found on Publication Page
13
Jack-In-The-Box model of gating in MscS. HR Malcolm, P Blount, JA Maurer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014.
Found on Publication Page
12
A Lack of Significant Lipid Interactions in the Open State of MSCS Implies a Jack-In-The-Box Type Channel Gating Mechanism. HR Malcolm, P Blount, JA Maurer Biophysical Journal 106 (2), 554a, 2014.
Found on Publication Page
In 2012
11
Exploring the Co-Mutlimerization of bCNG Channels. HR Malcolm, DE Elmore, JA Maurer Biophysical Journal 102 (3), 121a, 2012.
Found on Publication Page
10
Understanding The Structure-Function Relationships In The Mechanosensitive Channel Of Small Conductance (MscS) And Bacterial Cyclic Nucleotide Gated (bCNG) Ion Channels. HR Malcolm Washington University in St. Louis, 2012.
Found on Publication Page
9
Mechanosensitive behavior of bacterial cyclic nucleotide gated (bCNG) ion channels: Insights into the mechanism of channel gating in the mechanosensitive channel of small .... HR Malcolm, DE Elmore, JA Maurer Biochemical and biophysical research communications 417 (3), 972-976, 2012.
Found on Publication Page
8
The mechanosensitive channel of small conductance (MscS) superfamily: not just mechanosensitive channels anymore. HR Malcolm, JA Maurer Chembiochem 13 (14), 2037-2043, 2012.
Found on Publication Page
7
Ss-bCNGa: a unique member of the bacterial cyclic nucleotide gated (bCNG) channel family that gates in response to mechanical tension. HR Malcolm, YY Heo, DB Caldwell, JK McConnell, JF Hawkins, ... European Biophysics Journal 41, 1003-1013, 2012.
Found on Publication Page
In 2011
6
Exploring the response of bacterial cyclic nucleotide gated (bCNG) ion channels to mechanical stress. HR Malcolm, DE Elmore, JA Maurer Biophysical Journal 100 (3), 104a, 2011.
Found on Publication Page
5
Prediction and Verification of Critical Tension Sensing Residues in the E. coli Mechanosensitive Channel of Small Conductance (EC-MSCS). HR Malcolm, YY Heo, DE Elmore, JA Maurer Biophysical Journal 100 (3), 279a, 2011.
Found on Publication Page
4
Defining the role of the tension sensor in the mechanosensitive channel of small conductance. HR Malcolm, YY Heo, DE Elmore, JA Maurer Biophysical journal 101 (2), 345-352, 2011.
Found on Publication Page
In 2010
3
Identification and experimental verification of a novel family of bacterial cyclic nucleotide-gated (bCNG) ion channels. DB Caldwell, HR Malcolm, DE Elmore, JA Maurer Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (9), 1750-1756, 2010.
Found on Publication Page
In 2009
2
Functional and structural comparisons of MscS and bCNG ion channels. RC Guayasamin, HR Malcolm, JF Hawkins, A Maurer, DE Elmore ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 237, 465-465, 2009.
Found on Publication Page
1
Gating Of Bacterial Cyclic Nucleotide Gated (bCNG) Channels In Response To Membrane Tension. HR Malcolm, JF Hawkins, RC Guayasamin, DE Elmore, JA Maurer Biophysical Journal 96 (3), 256a, 2009.
Found on Publication Page
