Mark Goebl

Zhao, W., Breese, E., Bowers, A., Hoggatt, J., Broxmeyer, H.E., Goebl, M., Harrington, M.A. 2013. SIMPL enhancement of tumor necrosis factor?a dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function. PLoS ONE 8:e61123.

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Adler, J.J., Heller, B.L., Bringman, L.R., Ranahan, W.P., cockling, R.R., Goebl, M.G., Oh, M., Lim, H.S., Igham, R.J., Wells, C.D. 2012. Amot130 adapts Atrophin?1 Interacting Protein 4 to inhibit Yes-associated protein signaling and cell growth. J. Biol. Chem. 288: 15181-15193.

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Cocklin, R. and Goebl, M. 2011. Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34. PLoS One 6: e27099.

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Lass, A., Cocklin, R., Scaglione, K.M., Skowyra, M., Korolev, S., Goebl, M., and Skowyra, D. 2011. The loop-less tmCdc34 E2 mutant defective polyubiquitination activity in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2. Cell Div. 6: 7-25. PMID:21453497.

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Cocklin, R., Heyen, J., Larry, T., Tyers, M., and Goebl, M. 2011. New Insight Into the Role of the Cdc34 Ubiquitin-Conjugating Enzyme in Cell Cycle Regulation via Ace2 and Sic1. Genetics 187(3): 701-15. Epub 2010 Dec 31.

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Lin, L. Wagner, M.C., Cocklin, R., Kuzma, A., Harrington, M., Molitoris, B.A., Goebl M.G. 2011. The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases. Antimicrob. Agents Chemother.55(1): 246-54. Epub 2010 Oct 18. PMID:20956596

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Benson, E.A., Goebl, M.G., Yang, F.C., Kapur, R., McClintick, J., Sanghani, S., Clapp, D.W., Harrington, M.A. 2010. Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors. Exp. Hematol. 38(2): 71-81. Epub 2009 Nov 23. PMID:19941935

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Radivojac, P., Vacic, V., Haynes, C., Cocklin, R.R., Mohan, A., Heyen, J.W., Goebl, M.G., Iakoucheva, L.M. 2010. Identification, analysis, and prediction of protein ubiquitination sites. Proteins 78(2):365-80. PMID:19722269

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Lockett, Angelia, Goebl, M. and Harrington, M.A. 2008. Transient membrane recruitment of IRAK-1 in response to LPS and IL-1{beta} requires TNF R1. Am J Physiol Cell Physiol. 295(2):C313-23.

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Zhong, Y., Chen, J.Y., Heyen, J., Ott, L.W., Woods, C., Harrington, M.A., and Goebl, M.G. 2007. Data Management in Expression-based Proteomics. Biological Database Modeling. Published in Artech House, pp. 143-162.

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Ott, L.W., Resing, K.A., Sizemore, A.W., Heyen, J.W., Cocklin, R.R., Pedrick, N.M., Woods, H.C., Chen, J.Y., Goebl, M.G., Witzmann, F.A. and Harrington, M.A. (2007) Tumor Necrosis Factor-a and interleukin-1 induced cellular response: coupling proteomic and genomic information. J. Proteomic Sciences 6(6):2176-85.

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Luo, Y., Kwon, H-J., Montano, S., Georgiadis, M., Goebl, M. G., and Harrington, M. A. (2007) Phosphorylation of SIMPL modulates RelA associated NF-?B dependent transcription. Am J Physiol Cell Physiol. 292(3):C1013-23.

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Brutkiewicz, S, Mendonca, M., Stantz, K., Comerford, K., Bigsby, R., Hutchins, G., Goebl, M. and Harrington, M. (2007) The expression level of luciferase within tumor cells can alter tumor growth upon in vivo bioluminescence imaging. Luminescence.22: 221-228.

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Yan, Zhong, Jake Y. Chen, Josh Heyen, Lee W Ott, Cary Woods, Maureen A Harrington, and Mark G Goebl (2007) Data Management in Expression-based Proteomics, in Database Modeling in Biology: Theories and Practices. (In press).

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Wagner, M.C., Molnar, E.E., Molitoris, B.A., and Goebl, M.G. 2006. Loss of the homotypic fusion and vacuole protein sorting or Golgi-associated retrograde protein vesicle tethering complexes results in gentamicin sensitivity in the yeast Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 50: 587-595.

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Schweitzer, K., Cocklin, R., Garrett, L., Desai, F., and Goebl, M. 2005. The ubiquitin ligase SCFGrr1 is necessary for pheromone sensitivity in Saccharomyces cerevisiae. Yeast 22: 553-564.

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Kwon HJ, Breese EH, Vig-Varga E, Luo Y, Lee Y, Goebl MG, Harrington MA. 2004 Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL. Mol Cell Biol. 21:9317-26.

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Linghu B, Callis J, and Goebl MG. 2002. Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p. Euk. Cell 1: 491-494.

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Yu KY, Kwon HJ, Norman DAM, Vig E, Goebl MG, and Harrington MA. 2002. Cutting edge: Mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling. J. Immunol.169: 4075-4078.

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Hurteau JA, Allison BM, Brutkiewicz SA, Goebl MG, Heilman DK, Bigsby RM, and Harrington MA. 2001. Expression and subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in epithelial ovarian cancer. Gynecol. Oncol. 83: 292-298.

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Vig E, Green M, Liu YW, Yu KY, Kwon HJ, Tian J, Goebl MG, and Harrington MA. 2001. SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappa B activity. J. Biol. Chem. 276: 7859-7866.

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Smothers DB, Kozubowski L, Dixon C, Goebl MG, and Mathias N. 2000. The abundance of Met30p limits SCFMet30p complex activity and is regulated by methionine availability. Mol. Cell. Biol. 20: 7845-7852.

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Mathias N, Johnson S, Byers B, and Goebl M. 1999. The abundance of cell cycle regulatory protein Cdc4p is controlled by interactions between its F box and Skp1p. Mol. Cell. Biol. 19: 1759-1767.

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